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Eli Lilly · Global Obesity · 2025

Digital Experience Design & Strategy

Designing a global UX framework that scales across markets, respecting cultural, regulatory, and health literacy differences while maintaining experience design consistency.

Experience Design Global UX Competitive Intelligence Obesity Scalable Platform
Eli Lilly · Four markets · TANK Worldwide / Grey Health
One IA framework, deployed
across four regulatory markets
without a rebuild.
One architecture, deployed across 4 markets
Challenge
One obesity UX needed to work across four regulatory and cultural markets without fragmenting.
Approach
A global/flex-zone IA and stigma-reduction sequencing built around a named patient persona.
Outcome
Deployed across KSA, UAE, Germany, and Japan from one architecture — no per-market rebuild.
Final designHomepage and supporting pages
Full-length designed Obesity Is a Disease site pages

The stigma-reduction sequence in its designed form, inside the global/flex framework. Click to see the full pages. The tabs below show how it deployed across four markets without a rebuild.

Problem & insight
Product & UX approach
Decision log
Deliverables
Hindsight
All case studies →
From brief to reframed problem

The brief centered a named persona, Andrea: frustrated, stuck in a cycle of failed attempts, carrying stigma and worried about her health. Her emotional profile was the design constraint, and everything from the homepage sequence to the quiz prompts was calibrated to resolve her barriers before any clinical ask.

A global platform request concealed two distinct structural problems that needed to be solved sequentially.

Client brief

"Design a global obesity platform that can be adapted for each market — KSA, UAE, Germany, Japan — while maintaining brand and regulatory consistency."

Reframed UX problem

The brief frames this as adaptation. It is actually two problems. First, nobody had separated the elements that are non-negotiable globally from the genuine flex zones. Second, obesity is one of the most stigma-loaded conditions, so a patient with years of failed attempts and self-blame has to be met emotionally before any clinical ask. The challenge was global architecture plus stigma-aware sequencing, not localizing a standard pharma template.

The reframe produced the global/flex zone architecture and the stigma-reduction sequencing that opens the homepage.

Transferable to

Global wellness platforms & stigma-adjacent health conditions. Global constants with local flex zones suit any platform scaling across markets where a condition carries stigma. The stigma-reduction sequencing carries over to weight management, mental health, addiction support and other conditions where self-blame blocks engagement.

Key insight

Neither Novo Nordisk property addressed all five content pillars — and their approaches were mutually exclusive. ItsBiggerThan.com (emotional, community) missed biological causation and the HCP pathway. TruthAboutWeight.global (scientific) was weak on emotional validation and HCP conversion. Wegovy.com had an 84% bounce rate despite 970K monthly visits. Stigma was universal but showed up differently: social shame in Japan, religious self-judgment in KSA and UAE, personal-discipline failure in Germany.

Product & UX approach

I treated this as a global architecture problem with local sensitivity built in: non-negotiable IA and UX principles locked centrally, explicit flex zones for regional adaptation. AI-assisted research surfaced patterns and content gaps across all four markets. The five-screen Quiz Module, which generates a personalized discussion guide, was the most complex flex zone.

Key design decisions
Decision point Alternatives considered What we chose & why
Global architecture — template-based vs. principle-based
Single global template with market-specific content swaps (lowest technical overhead).
Principle-based architecture with global constants and explicit flex zones. A single template would have forced compromises that caused cultural missteps across very different stigma contexts.
Homepage opening — condition-first vs. stigma-reduction first
Lead with obesity as a medical condition — standard pharma DTC opening model.
Stigma-reduction first: four modules validate the patient’s experience before any biological framing, since self-blame is a primary barrier to medical content. MLR approved it as clinical barrier reduction.
Quiz interaction model — passive questionnaire vs. embedded learning prompts
Standard questionnaire generating a discussion guide at the end (simpler to build, no flow interruptions).
Learning prompts mid-flow: choosing “I continued to be hungry” immediately reframes it as biological resistance, not personal failure. Reframing at the moment of recognition, not afterward in a PDF, was the quiz’s highest-value move.
Figure 01 · DeliverableGlobal IA — site map framework
Section Content modules Count
0.0 Home It's time for a real change · It's not your fault · Obesity impacts life · Break free from the burden 4 modules
1.0 Understanding Obesity What is obesity? · What makes weight loss so difficult? 2 modules
2.0 Weight Management Options Lifestyle changes · Anti-obesity medications · Surgery · Where are you on your journey? 4 modules
3.0 Weight Loss Journeys Stories and experiences · Expert advice 2 modules
4.0 Talk to Your Doctor Have a different conversation with your doctor · Get your discussion guide 2 modules
+ 6 footer utility pages — Home, Privacy Policy, Terms of Use, Contact, 404 Error, 500 Error
4
Core sections
12
Content modules
Global
IA framework — adaptable across KSA, UAE, Germany, Japan

The site map sets the page hierarchy and content groupings that had to stay consistent across all markets. The homepage opens with four stigma-reduction modules before routing patients into four pathways.

It fixed which elements were non-negotiable globally, giving regional teams a clear brief instead of an open one and reducing late-stage drift.

Framework A · UX Methodology Stigma-Reduction UX Framework

Four homepage modules form the global constant zone, sequenced to resolve shame, attribution, stakes and agency before any clinical content. Select a module to expand.

Module 1
Activation
"It's time for a real change"
Names urgency without blame — opens the frame
Module 2
Attribution shift
"It's not your fault"
Transfers causal responsibility from patient to biology
Module 3
Stakes elevation
"Obesity impacts life"
Reframes weight as a health condition with systemic consequences
Module 4
Agency return
"Break free from the burden"
Hands control back to patient — primes action readiness
Module 1 · Activation — "It's time for a real change"
Behavioral function

Creates an opening without assigning blame. The patient must feel addressed, not judged, before any information has value.

Why it's a global constant

The emotional barrier it resolves — shame-avoidance — is culturally invariant. Localising this module risks softening the activation signal.

Gate to next module

Patient has accepted the premise that change is possible. Attribution of cause is still unresolved — must be addressed next.

Global constant Emotional barrier: shame Mechanism: urgency framing

Sequence constraint: modules appear in this order in every market build, because reordering collapses the behavioral arc. Flex zones begin at section two of the site IA.

Framework B · UX Methodology Progressive Disclosure IA Framework

Five-section readiness ladder. Each section has a gate condition that must be met before the next has behavioral value. Select a section to expand.

Homepage
Stigma resolved, biology framed
Understanding obesity
Condition understood, not feared
Weight management options
Treatment landscape mapped, HCP role clear
Weight loss journeys
Social proof established, hesitation addressed
Talk to your doctor

Homepage — emotional foundation

Permission to engage at all. Shame and self-blame are resolved before any clinical information.

Four stigma-reduction modules in fixed sequence, a soft CTA, and no clinical content until the arc completes.

Global constantModule sequence fixedSoft CTA only

Understanding obesity — condition education

Acceptance of the medical framing, so treatment options carry credibility.

Core: biology, comorbidities, systemic impact. Flex: comorbidity emphasis by market.

Core: global constantFlex: comorbidity emphasis

Weight management options — treatment landscape

Treatment seen as a legitimate, multi-modal space, with HCP guidance as context, not gatekeeping.

Core: treatment categories and the role of medical management. Heavy flex: options, regulatory references and reimbursement.

Core: treatment framingFlex: options & regulatory refsFlex: reimbursement context

Weight loss journeys — social proof layer

Confidence that people like them have navigated this, lowering the barrier to an HCP conversation.

High flex. Stories reflect market demographics and local emotional barriers; voice and tone may flex.

Core: social proof functionFlex: persona, voice & toneFlex: story selection

Talk to your doctor — action conversion

Concrete action: the CTA is now a low-friction next step, not a leap.

Core: HCP conversation framing and preparation tools. Flex: HCP-finding tools, entry points and CTA phrasing by market access model.

Core: conversation framingFlex: HCP-find toolsFlex: CTA phrasing
Global constant — no localisation
Flex zone — market-level adaptation permitted
Gate condition — must be met to preserve journey integrity
Figure 02 · Wireframe · Pre-production
Mobile Wireframes R10 — six-artboard spread showing full five-section patient journey

Mobile wireframes R10: a six-artboard, mid-fidelity spread of the five-section patient journey at 375px, including the Quiz Module. Its nine questions carry embedded learning prompts. Selecting an answer such as “I continued to be hungry” reframes it as biological resistance mid-flow, and the result downloads as a PDF discussion guide for HCP conversations. Copy is lorem placeholder; the deliverable is the structure, interaction design and sequencing. Pre-MLR working copy.

Seven validated mobile layouts gave regional teams reference implementations to adapt, not blank canvases — cutting per-market design time without sacrificing local precision.

Role
Director, UX Strategy, TANK Worldwide / Grey Health — global UX strategy & experience design lead: IA, content hierarchy, global-to-local framework
Team
Led a multi-functional team
Collaboration
Led agency-side across UX, strategy and global delivery before aligning with Lilly’s platform owners and four regional teams. Locking global principles first let local adaptation proceed without escalation.
Deliverables
UX/SEO competitive audit (5 competitors), global IA, site map, mobile wireframes (R10), biological resistance visual (4 iterations), quiz module with learning prompt architecture, UX layouts, MLR-approved platform
Regulatory context
MLR · multi-market regulatory (KSA, UAE, Germany, Japan)
Industry
Pharmaceuticals · Global health · Unbranded DTC
Where I'd tighten the system

The architecture scaled well across four markets. Local teams still needed a clearer signal, such as a governance decision tree telling them whether they were in a flex zone or a global constant, rather than catching drift in late-stage review. I’d also point the AI research layer at regional patient-voice content earlier. We used it mainly for competitive pattern analysis, and applying it to cultural sensitivity would have sharpened the flex zones.