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Eli Lilly · Clinical Trials

Beacon Platform — Patient Experience Strategy & IA

Reframing clinical trial participation as a guided decision journey — UX strategy and IA from discovery through enrollment in a regulated research environment.

UX Strategy Information Architecture Decision-Support Design Clinical Trials FDA · MLR
Eli Lilly · Beacon Platform · Oncology
From last resort
to first choice.
MLR-ready · 3-stage progressive disclosure
Challenge
Problem reframe
UX approach
Decision log
Research → insight
Deliverables
Hindsight
The challenge

Lilly's oncology clinical trials platform was fighting a specific and well-documented patient belief: that clinical trials are a last resort — something you consider after every other treatment option has failed. The engagement plan named this as the primary barrier: "the strong preconceived myths and mindset around clinical trials as a last-option for cancer therapy." The platform had to dismantle that belief before it could ask patients to consider enrollment.

Three distinct audiences were identified, each with a different primary barrier. Patients carried the last-resort myth. Caregivers lacked confidence to advocate for a clinical trial option on day one of a diagnosis. The general population simply didn't think of clinical trials as an immediate option following diagnosis. The existing platform addressed none of these barriers structurally — it was built as a trial inventory browser, not a decision-support experience.

The information architecture treated the enrollment decision like a marketing conversion. What was needed was a guided UX decision framework built around three overlapping patient journeys with different entry points, emotional states, and decision-support needs — not a brochure.

My role: I led UX strategy and information architecture for the Beacon clinical trial participation platform, working directly with clinical, regulatory, and digital teams within Lilly's enterprise design system. I owned the experience framework, journey design, decision support models, and content hierarchy from discovery through enrollment.

Working across teams

Led agency-side, coordinating across UX, strategy, and content internally before aligning with Lilly's clinical, regulatory, and digital teams. Every structural decision was negotiated across both organizations before it entered wireframe stage. By the time the progressive disclosure model reached wireframes, both teams had already signed off on the logic.

From brief to reframed problem

The most important design decision in this project happened before any design work started — reframing what the actual problem was.

Client brief

"Build a platform that educates patients about Lilly clinical trials and helps them find trials they may be eligible for."

Reframed UX problem

The architecture treats enrollment like a marketing funnel. But patients aren't making a purchase decision — they're making a medical one, under uncertainty, often in a health crisis. The platform needs to be built around how people actually make high-stakes health decisions, not around trial inventory search. The right model is a guided decision journey, not a discovery engine.

This reframe shifted the IA from a search-and-filter taxonomy to a three-stage progressive disclosure model — awareness, consideration, action — structured around patient readiness, not content volume.

Transferable to

Digital health patient engagement & DTx onboarding. The three-stage model applies to any health platform where users must build understanding before they can meaningfully act — patient recruitment, condition management apps, and health-tech enrollment flows face the identical structural problem. Any platform that leads with action before establishing readiness will reproduce the same drop-off pattern.

UX approach

I defined a UX framework that mapped what patients needed to understand, feel, and do at each stage before asking them to act. Three stages — awareness, consideration, action — each designed as a standalone UX module that scaled without requiring structural rebuilds.

I owned the IA, content hierarchy, and decision support design across the full platform — translating clinical and regulatory requirements into a patient experience architecture that progressive disclosure logic could hold together across every page.

The phased delivery strategy balanced launch urgency with long-term scalability. Phase 1 established core experience across five sections. Phase 2 expanded on that foundation without requiring architectural rework.

Key design decisions
Decision point Alternatives considered What we chose & why
IA model — search-first vs. journey-first
Trial search and filter as primary navigation — patient enters condition and location, sees matching trials.
Journey-first progressive disclosure. Patients in consideration aren't ready to evaluate trial specifics until foundational understanding is established.
Clinical content — verbatim vs. plain language
Expose inclusion/exclusion criteria verbatim from protocol. Legally safest; no interpretation risk.
Plain language primary with clinical language in footnote register. Verbatim criteria actively harmed comprehension — MLR approved the translation layer.
Phased launch rationale — scope management vs. SEO infrastructure
Frame Phase 1 as a scope reduction — deliver less at launch to control quality and timeline.
Phase 1 splash page designed as deliberate SEO infrastructure: building backlink history and search credibility before Phase 2 launched. News sites and blogs linking to Phase 1 would accumulate domain authority that Phase 2 inherited. Also mitigated brand impersonation risk in the interim period. Scope management was a secondary benefit — search equity was the primary one.
Research → insight → recommendation
Research input
Competitive audit of 8 clinical trial patient platforms + audience barrier mapping

Heuristic review of trial platform IA across pharma and research network sites. AI-augmented pattern extraction across structural models, content hierarchies, and patient pathway design. Audience barrier mapping across three distinct user groups: patients (last-resort myth), caregivers (day-one advocacy confidence gap), and general population (awareness deficit).

Key insight
Every platform reinforced the last-resort myth by leading with enrollment

All eight platforms surfaced eligibility criteria and enrollment CTAs at the awareness stage — before addressing the belief that trials are only for patients who've run out of options. None modeled the cognitive and emotional arc of a patient newly navigating a trial decision in an oncology context. The IA structure of every platform assumed a patient already persuaded; none built the persuasion.

UX recommendation
Myth-first architecture: address the last-resort belief before surfacing trial content

Stage 1 (Awareness): normalize clinical trials as a first-choice option — directly address misconceptions and realities before any trial inventory is shown. Stage 2 (Consideration): evaluate fit in plain language across patient, caregiver, and general population entry points. Stage 3 (Action): eligibility screening and enrollment pathway.

Transferable to

Digital health patient engagement & DTx onboarding. The three-stage model applies to any health platform where users must build understanding before they can meaningfully act — patient recruitment, condition management apps, and health-tech enrollment flows face the identical structural problem.

Figure 01 · DeliverablePatient journey map — phased site architecture
Phase Strategy
Phase 1
Launch Campaign Site
Rapid execution, scalable foundation. 1–2 robust pages with varied content modules — builds organic search reputation and serves as the platform for Phase 2 expansion.
Phase 2
Data-Driven Expansion
Informed by Phase 1 behavior. Leverages backlink history and real patient engagement data to expand into audience-specific dedicated pages.
P1 site architecture — Home + 5 sections
1.0 What Are Clinical Trials2 sub-pages
2.0 Benefits of Clinical Trials2 sub-pages
3.0 Resources and Guides1 sub-page
4.0 Clinical Trial Search1 sub-page
5.0 Clinical Trial Questions & FAQs1 sub-page
2
Phased builds
5
Core pages
8
Content blocks

Patient journey map & UX site architecture — phased UX delivery strategy for the Beacon platform, balancing launch urgency with long-term scalability. Phase 1 established core experience across five sections, each designed as a standalone UX module while serving as the foundation for Phase 2 expansion.

The journey map shifted the internal conversation from 'what content do we build' to 'what does the patient need to understand before they can act' — establishing the progressive disclosure model as the organizing logic before any design work began.

Figure 02 · DeliverableIA audit — patient decision journey
Audience Primary barrier
PatientTrials perceived as last-option therapy — not a first-choice treatment path upon diagnosis.
CaregiverLack of confidence to elevate a trial option for a loved one's treatment on Day 1.
Newly DiagnosedTrials not an immediate thought following diagnosis — awareness gap at the highest-urgency moment.
General PopulationLack of identification and urgency to seek a trial — category consideration near zero.
Primary finding
The IA gap was structural, not informational. A single-phase site attempted to serve all four audience barriers simultaneously. A phased architecture was required: P1 to establish organic search credibility and broad topic coverage; P2 to expand into audience-specific dedicated pages driven by real engagement data.
Audit dimension P1 P2 Priority
Audience barrier coverage GAPEXPANDCRITICAL
Progressive disclosure logic GAPRESOLVESCRITICAL
Trial search tool placement HighHighHigh
Interactive content integration HighHighHigh
MLR regulatory sequencing CRITICALCRITICALCRITICAL
HCP conversation pathway P2HighHigh
2
Phased IA builds
4
Audience barriers
11
Content blocks mapped
MLR ✓
Regulatory aligned

Information architecture & experience design framework — translated the UX site architecture into a full information hierarchy model, mapping how clinical content is sequenced across all trial types to support progressive patient understanding from awareness through enrollment.

The IA framework was used directly by the MLR team to evaluate content placement decisions — eliminating a separate regulatory translation layer and accelerating the review cycle.

Figure 03 · Wireframe · Pre-productionBeacon_WF_R19
Beacon Platform Desktop Wireframes R19 — five-section spread

Desktop wireframes R19 — five-section spread showing the complete Beacon patient journey at desktop viewport. Sections in sequence: Homepage (awareness entry, cancer-to-trials narrative hook, enrollment benefits, find a trial tool), Clinical Trials Overview (What Are Trials, Potential Benefits, FAQ accordion), Misconceptions & Realities (directly addressing the last-resort myth — the primary patient barrier identified in the engagement plan), Trial Detail (eligibility criteria in plain-language UX treatment, common questions, risk disclosure integration), Resources & Guides (downloadable decision aids, Questions to Ask Your Doctor), and Find a Trial Near You (trial-matching interface). Regulatory disclosures designed as structural content components throughout — not footer or modal interrupts. Built within the Lilly Design System. Pre-MLR working copy; structural hierarchy and progressive disclosure logic are the deliverable.

Desktop wireframes at R19 reflected a fully negotiated IA — structural decisions had been validated with clinical, regulatory, and digital stakeholders before this delivery, so the wireframes moved directly to MLR submission.

Figure 04 · MLR-approved artifact
Beacon Platform — Produced Site Pages

MLR submission artifacts — three representative pages from the complete Beacon platform, designed within Lilly's editorial visual language: dark cinematic hero photography and serif display type chosen deliberately to read as journalism rather than pharma marketing, reinforcing the myth-first tone before any clinical content appears. Pages illustrate UX content hierarchy and progressive disclosure design across three distinct stages of the patient decision journey. Clinical references and regulatory disclosures integrated as structural UX elements.

Three produced pages illustrating the progressive disclosure model in action — used as architecture proof in the MLR submission to demonstrate that regulatory disclosures could function as structural UX elements rather than modal interrupts.

Role
UX strategy and IA lead
Deliverables
Audience barrier mapping (3 segments), journey map, IA framework, desktop wireframes (R19), MLR-approved site pages — built within Lilly Design System
Regulatory context
FDA · MLR · Lilly enterprise design system
Industry
Pharmaceuticals · Oncology · Clinical research
If I ran this again

The progressive disclosure model held across the full platform. Two things I'd refine: first, instrument a readiness signal at entry so patients who arrive already informed — via HCP referral or prior trial experience — can branch at Stage 1 rather than moving through awareness linearly. Second, start the plain-language eligibility negotiation with MLR in the strategy phase, not mid-design. Getting there earlier buys timeline and produces a sharper Stage 2.